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81.
Joanne Ng MD PhD Elisenda Cortès-Saladelafont MD Lucia Abela MD Pichet Termsarasab MD Kshitij Mankad FRCR Sniya Sudhakar FRCR Kathleen M. Gorman MD Simon J.R. Heales PhD Simon Pope PhD Lorenzo Biassoni MSc FRCP FEBNM Barbara Csányi MD John Cain FRCR PhD Karl Rakshi MBChB Helen Coutts MD Sandeep Jayawant MD FRCPCH Rosalind Jefferson MBBS PhD Deborah Hughes MSc Àngels García-Cazorla MD PhD Detelina Grozeva PhD F. Lucy Raymond MD PhD Belén Pérez-Dueñas MD PhD Christian De Goede MD Toni S. Pearson MD Esther Meyer PhD Manju A. Kurian MD PhD 《Movement disorders》2020,35(8):1357-1368
82.
83.
Ankur Patel Pranav Mandovra Tanveer Majeed Roy V Patankar 《Asian journal of endoscopic surgery》2019,12(2):181-184
Tailgut cyst is an uncommon developmental anomaly arising from the embryonic hindgut in the retrorectal space. The patient frequently is asymptomatic or has vague perineal complaints that pose a diagnostic dilemma. Moreover, the patient is often misdiagnosed and therefore mismanaged. MRI is the investigation of choice for diagnosis. After the diagnosis is established, complete surgical excision is required to alleviate patient discomfort and to prevent complications such as infection, malignant transformation, and recurrence. Proper clinical examination and imaging not only establish the accurate diagnosis but also help in determining the best surgical approach for the patient (anterior abdominal, posterior sacral perineal, or combined approach). We hereby report a case of recurrent tailgut cyst managed with a combined anterior laparoscopic and perineal approach. 相似文献
84.
V. Sawlani N. Davies M. Patel R. Flintham C. Fong G. Heyes G. Cruickshank N. Steven A. Peet A. Hartley H. Benghiat S. Meade P. Sanghera 《Clinical oncology (Royal College of Radiologists (Great Britain))》2019,31(1):41-49
Aims
Following stereotactic radiosurgery (SRS), brain metastases initially increase in size in up to a third of cases, suggesting treatment failure. Current imaging using structural magnetic resonance imaging (MRI) cannot differentiate between tumour recurrence and SRS-induced changes, creating difficulties with patient management. Combining multiparametric MRI techniques, which assess tissue physiological and metabolic information, has shown promise in answering this clinical question.Materials and methods
Multiparametric MRI techniques, including spectroscopy, diffusion and perfusion imaging, were used for the differentiation of radiation-related changes and tumour recurrence after SRS for intracranial metastases in six cases. All patients presented with enlargement of the treated lesion, an increase in perilesional brain oedema and aggravation or appearance of neurological signs and symptoms from 7 to 29 weeks after primary treatment.Results
Multiparametric imaging helped to differentiate features of tumour progression (n = 4) from radiation-related changes (n = 2). A low apparent diffusion coefficient (ADC) <1000 × 10?6 mm2/s, high relative cerebral blood volume (rCBV) ratio > 2.1, high choline:creatine (Cho:Cr) ratio > 1.8 suggested tumour recurrence. A high ADC > 1000 × 10?6 mm2/s, low rCBV ratio < 2.1, Cho:Cr ratio < 1.8 suggested SRS-induced radiation changes. Multiparametric MRI diagnosis was confirmed by histology or radiological and clinical follow-up.Conclusion
Multiparametric MRI was helpful in the early identification of radiation-related changes and tumour recurrence and may be useful for monitoring treatment changes in intracranial neoplasms after SRS treatment. 相似文献85.
86.
Arunaloke Chakrabarti Prashant Sood Shivaprakash M. Rudramurthy Sharon Chen Joseph Jillwin Ranganathan Iyer Ajanta Sharma Belgode Narasimha Harish Indranil Roy Anupma J. Kindo Deepinder Chhina Jayanthi Savio Deepak Mendiratta Malini R. Capoor Shukla Das Anita Arora Jagdish Chander Immaculata Xess Appalaraju Boppe Ujjwayini Ray Ratna Rao Vandana Kalwaje Eshwara Sangeeta Joshi Atul Patel Raman Sardana Anjali Shetty Umabala Pamidimukkala for the SIHAM Candidemia Network 《Mycoses》2020,63(11):1149-1163
87.
Tessa Timmers Rik Ossenkoppele Denise Visser Hayel Tuncel Emma E Wolters Sander CJ Verfaillie Wiesje M van der Flier Ronald Boellaard Sandeep SV Golla Bart NM van Berckel 《Journal of cerebral blood flow and metabolism》2020,40(12):2464
The aim of this study was to investigate the test–retest (TRT) repeatability of various parametric quantification methods for [18F]Flortaucipir positron emission tomography (PET). We included eight subjects with dementia or mild cognitive impairment due to Alzheimer’s disease and six cognitively normal subjects. All underwent two 130-min dynamic [18F]Flortaucipir PET scans within 3 ± 1 weeks. Data were analyzed using reference region models receptor parametric mapping (RPM), simplified reference tissue method 2 (SRTM2) and reference logan (RLogan), as well as standardized uptake value ratios (SUVr, time intervals 40–60, 80–100 and 110–130 min post-injection) with cerebellar gray matter as reference region. We obtained distribution volume ratio or SUVr, first for all brain regions and then in three tau-specific regions-of-interest (ROIs). TRT repeatability (%) was defined as |retest–test|/(average (test + retest)) × 100. For all methods and across ROIs, TRT repeatability ranged from (median (IQR)) 0.84% (0.68–2.15) to 6.84% (2.99–11.50). TRT repeatability was good for all reference methods used, although semi-quantitative models (i.e. SUVr) performed marginally worse than quantitative models, for instance TRT repeatability of RPM: 1.98% (0.78–3.58) vs. SUVr80–100: 3.05% (1.28–5.52), p < 0.001. Furthermore, for SUVr80–100 and SUVr110–130, with higher average SUVr, more variation was observed. In conclusion, while TRT repeatability was good for all models used, quantitative methods performed slightly better than semi-quantitative methods. 相似文献
88.
Kolanko Magdalena Win Zarni Patel Neva Malik Omar Carswell Christopher Gontsarova Anastassia Nicholas Richard Perry Richard Malhotra Paresh 《Journal of neurology》2020,267(11):3268-3273
Journal of Neurology - Cognitive dysfunction affects 40–60% of individuals with multiple sclerosis (MS). The neuropsychological profile commonly consists of a subcortical pattern of deficits,... 相似文献
89.
Magon Stefano Tsagkas Charidimos Gaetano Laura Patel Raihaan Naegelin Yvonne Amann Michael Parmar Katrin Papadopoulou Athina Wuerfel Jens Stippich Christoph Kappos Ludwig Chakravarty M. Mallar Sprenger Till 《Journal of neurology》2020,267(5):1536-1546
Journal of Neurology - Volume loss in the deep gray matter (DGM) has been reported in patients with multiple sclerosis (MS) already at early stages of the disease and is thought to progress... 相似文献
90.
Elfil Mohamed Ahmed Nada Alapati Amritha Bahekar Rucha Kandil Mohamed Kim Christine Schaefer Sara Tinaz Sule Patel Amar S. de Figueiredo John M. Louis Elan D. Koo Brian B. 《Journal of neurology》2020,267(4):966-974
Journal of Neurology - We aimed to determine suicide risk and lifetime suicidal ideation in Parkinson disease (PD) patients versus controls and how depression, demoralization, and insomnia are... 相似文献